This Week in PNAS

In the PNAS Early Edition this week, researchers at the University of Victoria and the National Institute of Allergy and Infectious Diseases report that they've inserted nine "essential genes" from Arctic bacteria into mammalian pathogenic bacteria "to construct stable, temperature-sensitive bacterial vaccines." One ligA gene, the team writes, "was shown to render Francisella tularensis, Salmonella enterica, and Mycobacterium smegmatis temperature-sensitive." Three tempe

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Polygamy amplified a rare genetic disease in area near Arizona-Utah border, BBC Future reports.

Genetic ancestry testing led one woman to learn that her father and another baby boy had been switched at birth, the Washington Post reports.

Simple de-identification methods can protect information in a database from attackers, a new study suggests.

In Science this week: approach to visualize chromatin structure in nuclei, and more.