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Researchers in China report in PNAS this week their method for "constructing ultrahigh-density linkage maps composed of high-quality SNPs based on low-coverage sequences of recombinant inbred lines." The team's first step was to elucidate high-quality SNPs and perform a Bayesian inference in order to genotype the lines in the mapping populations using the SNPs, assisted by a hidden Markov model.

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