This Week in PNAS

In the Early Edition of PNAS this week, researchers identify 119 genes as potential drug targets — a finding they derived from a function-based gene identification using an shRNA library they constructed. The library contains about 150 shRNAs per gene investigated and was composed in an inducible lentiviral vector, enabling the propagation of growth-inhibiting shRNAS.

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.