This Week in PNAS: Apr 6, 2010

Apr 06, 2010

In the Early Edition of PNAS this week, researchers identify 119 genes as potential drug targets — a finding they derived from a function-based gene identification using an shRNA library they constructed. The library contains about 150 shRNAs per gene investigated and was composed in an inducible lentiviral vector, enabling the propagation of growth-inhibiting shRNAS.

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