This Week in PNAS | GenomeWeb

This Week in PNAS

In PNAS this week, investigators in Germany and the UK show that translation of the proto-oncogene c-Myc is repressed by miR-24c following etoposide-induced DNA damage. "While miR-34c is induced by p53 following DNA damage, we show that in cells lacking p53 this is achieved by an alternative pathway which involves p38 MAPK signaling to MK2," they write, adding that their data reveal c-Myc as a major target of miR-34c.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

Two manuscript pages handwritten by Charles Darwin are going on the auction block, according to the Los Angeles Times.

In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.