This Week in PNAS

In the PNAS Early Edition this week, researchers describe their discovery that amyloidogenic light chain (AL-LC) proteins induce oxidative stress, cellular dysfunction, and apoptosis in isolated adult cardiomyoctes through the activation of p38α mitogen-activated protein kinase. The team found the AL-LC-induced p38 activation to be independents of the upstream MAPK kinase, MKK3/6.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.