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In this week's PNAS, Wayne State University researchers report on a way to monitor DNA synthesis at the single base-pair level. By looking at single-molecule Förster resonance energy transfer, researchers led by David Rueda were able to see the incorporation of three nucleotides by the Escherichia coli DNA polymerase I. They then noted that the FRET efficiency drops off and then returns the expected level.

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In a letter, about two dozen researchers criticize the World Health Organization investigation into the origins of SARS-CoV-2 and call for a new inquiry, the Wall Street Journal reports.

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