This Week in PNAS

In a paper published this week in PNAS, University of Edinburgh scientists show that "the majority of S. aureus isolates from broiler chickens are the descendants of a single human-to-poultry host jump," which they believe happened about 38 years ago, by a subtype of a lineage from Poland. This ST5 clade has adapted to its new host through acquiring new mobile elements and inactivating several important human disease genes, they say.

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.