This Week in PNAS

In work appearing in this week's edition of PNAS, Tel Aviv University's Ronen Borenstein and Niza Frenkel describe single-step production of viral BACs of the 160-kb human herpes virus 6A. Their method of cloning, they say, is "independent of intracellular recombinations and DNA packaging constraints" and is "especially attractive for viruses that replicate inefficiently and for viruses propagated in suspension cells."

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NPR reports that with medical data being big business, some companies want to get patients involved.

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.