This Week in PNAS | GenomeWeb

This Week in PNAS

In PNAS this week, Stanford University's Sebastian Maerkl and Stephen Quake study the evolution of transcription factors. In this work, they created all possible 95 single-point mutations of five DNA-contacting residues of Max, a human helix–loop–helix transcription factor, and then measured the DNA binding of each mutant.

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In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.