This Week in PNAS

In PNAS this week, Stanford University's Sebastian Maerkl and Stephen Quake study the evolution of transcription factors. In this work, they created all possible 95 single-point mutations of five DNA-contacting residues of Max, a human helix–loop–helix transcription factor, and then measured the DNA binding of each mutant.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.