This Week in PNAS

In the current issue of PNAS, plant biologists show that SET7, a known histone methyltransferase, is involved in regulating the stability of DNA methyltransferase (DNMT1), which has a role in regulating cytosine DNA methylation in mammalian cells. SET7 interacts with DNMT1, they found, and overexpression of SET7 leads to decreased DNMT1 levels, while knockdown of SET7 stabilizes DNMT1.

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A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.

Newsday reports that breast cancer genetic testing guidelines for are out of date and may miss individuals.

In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.