This Week in PNAS

In the early edition of the Proceedings of the National Academy of Sciences, investigators from the US and Pakistan present findings from their transcriptome sequencing study of metastatic breast cancer cells that had or had not been treated with the chemotherapeutic drug paclitaxel. Using single-cell and bulk RNA sequencing, the team characterized gene expression profiles in untreated cells, cells that have become resistant to paclitaxel, and cells that are stressed by paclitaxel exposure.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.