This Week in PNAS

In the early edition of the Proceedings of the National Academy of Sciences, investigators from the US and Pakistan present findings from their transcriptome sequencing study of metastatic breast cancer cells that had or had not been treated with the chemotherapeutic drug paclitaxel. Using single-cell and bulk RNA sequencing, the team characterized gene expression profiles in untreated cells, cells that have become resistant to paclitaxel, and cells that are stressed by paclitaxel exposure.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.