This Week in PNAS

In the Proceedings of the National Academy of Sciences this week, Graham Lord at King's College London has led a study that checked into the genetic factors behind the differentiation of CD4+ T helper cells. In searching for target genes of the transcription factors T-bet and GATA-3, which direct the differentiation of Th cells into Th1 and Th2 cells, they created a genomic map of T-bet and GATA-3 binding in primary human T cells.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.