This Week in PNAS

In the early edition of the Proceedings of the National Academy of Sciences, researchers from Israel and the US report on results of a population-based screening effort aimed at estimating breast or ovarian cancer risk amongst BRCA1 or BRCA2 gene mutation carriers. The team started by screening healthy Ashkenazi Jewish men to narrow in on families prone to mutations in the two risk genes, before genotyping BRCA1 and BRCA2 mutations in female relatives from more than 100 families.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.