This Week in PNAS

Researchers from Stanford and Yale Universities report on an approach that combines short and long read sequence data to produce a personal transcriptome with allele-specific resolution. Using Pacific Biosciences and Illumina sequencing technologies, the team sequenced transcripts from lymphoblastoid cell lines that had been generated with samples from three individuals in a parent-child trio.

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CNBC reports that Amazon invested in the startup Grail as it sees an opportunity for its cloud computing company in genomics.

Lawrence Krauss writes at Slate that science is needed for good public policy and should not be ignored.

Researchers are working on re-making the yeast genome from scratch, according to the Associated Press.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.