This Week in PNAS

In PNAS, there's no shortage of clinically oriented research. This paper from senior author Jeremy Nicholson and team use pharmacometabonomics to identify metabolic interactions in humans that depend on their microbiome; they urge an assessment of these microbial communities as "an integral part of pharmaceutical development and of personalized health care." Ian Wilson offers a commentary.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.