This Week in PNAS

A group of Australian researchers previously found that Wolbachia, an insect endosymbiont, manipulates host microRNA levels so that it is maintained in Aedes aegypti, the dengue virus vector. This week, they report in the Proceedings of the National Academy of Sciences that Wolbachia represses the expression of AaDnmt2, the Ae. aegypti DNA methyltransferase gene, while the dengue virus induces its transcription.

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This Week in PNAS

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Rob Knight writes at Scientific American that microbiome studies are about to break out of the laboratory.

Harold Varmus, the director of the National Cancer Institute, has announced that he is stepping down after nearly five years.