This Week in PNAS

In the early, online edition of the Proceedings of the National Academy of Sciences, a Johns Hopkins University- and University of Iowa-led team describes a genome engineering scheme centered on a modified version of the piggyBac transposase enzyme and its corresponding transposon, which were used in combination with zinc finger proteins in the proof-of-principle study.

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23andMe's Anne Wojcicki ponders DNA and what it means to be human in a New York Times essay.

A new estimate places the last universal common ancestor to life on Earth as living 3.9 billion years ago, Inverse reports.

In PNAS this week: retinitis pigmentosa gene therapy, role of microbiome in growth stunting, and more.

Bloomberg reports that researchers and drug companies are modeling anti-obesity treatments after the rare genetic condition essential fructosuria.