This Week in PNAS

In the early, online edition of the Proceedings of the National Academy of Sciences, a UK team describes gene expression shifts in blood samples from people deprived of sufficient shuteye. Array-based transcripome profiling on samples from 26 individuals involved in week-long sleep restriction experiments indicated that insufficient snoozing can lead to higher- or lower-than-usual expression of hundreds of genes in the blood, the researchers report.

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Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.