This Week in PNAS

A Memorial Sloan-Kettering Cancer Center-led team presents a model for doing integrated analyses of cancer genomes in a study slated to appear online this week in the Proceedings of the National Academy of Sciences. Using data from the Cancer Cell Line Encyclopedia and The Cancer Genome Atlas, the researchers demonstrated that their statistical framework — called iCluster+ — accurately classified hundreds of cancer cell lines by sites of origin, subgroup, and so on.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.