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This Week in PNAS

In the PNAS Early Edition this week, researchers in New Hampshire and Ohio report that cofactor molecules are an integral part of infectious prions. The team shows that withdrawal of cofactor molecules during serial propagation of purified recombinant prions causes a reduction in specific infectivity and an adaptation of prions containing misfolded proteins.

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Mainichi reports that 43 percent of Japanese individuals said they did not want to eat agricultural products that had been modified using gene-editing tools.

Two US Department of Agriculture research departments are moving to the Kansas City area, according to the Washington Post.

Slate's Jane Hu compares some at-home genetic tests to astrology.

In PLOS this week: analysis of polygenic risk scores for skin cancer, chronic pain GWAS, and more.