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In the PNAS Early Edition this week, researchers in New Hampshire and Ohio report that cofactor molecules are an integral part of infectious prions. The team shows that withdrawal of cofactor molecules during serial propagation of purified recombinant prions causes a reduction in specific infectivity and an adaptation of prions containing misfolded proteins.

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NPR reports that vaccine developers are working on SARS-CoV-2 vaccines that are easier to store or administer than the current crop.

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