This Week in PNAS

In the PNAS Early Edition this week, researchers in New Hampshire and Ohio report that cofactor molecules are an integral part of infectious prions. The team shows that withdrawal of cofactor molecules during serial propagation of purified recombinant prions causes a reduction in specific infectivity and an adaptation of prions containing misfolded proteins.

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Gene drives might run into biological resistance, the Economist reports.

Forensic experts exhumed painter Salvador Dalí's body to collect DNA for a paternity test, CBS News reports.

Yale Environment 360 writes that synthetic and conservation biologists aren't always on the same wavelength, but they are trying to reach an understanding.

In Science this week: full CRISPR locus integration complex structure, and more.