This Week in PNAS

A consortium of scientists from Yale and EMBL, among others, used high-resolution analysis to study the genetics of Down syndrome in a paper published in the early online edition of PNAS this week. The scientists created a genetic map for 30 patients with rare segmental trisomies of various regions of HSA21 and found regions of 1.8 Mb -16.3 Mb likely to be involved in the development of eight of the cases, confirming the role of a single consensus region in causing severe Down syndrome.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.