This Week in PNAS

In a paper appearing in this week's PNAS Early Edition, researchers at Cornell University "present a proof-of-principle demonstration for a new method using a nanofluidic device that combines real-time detection and automated sorting of individual molecules based on their epigenetic state." For this demonstration, the researchers report that their technology showed up to 98 percent accuracy in molecule sorting and that it "achieved postsorting sample recovery on femtogram quantities

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.