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In this week's PNAS Early Edition, researchers at the Cold Spring Harbor Laboratory in New York and their collaborators present evidence to suggest that "large cancer-associated deletions can produce phenotypes distinct from those arising through loss of a single TSG [tumor-suppressor gene], and as such should be considered and studied as distinct mutational events." The team tested its hypothesis — that large chromosomal deletions "can arise from selective pressure to attenuate the activity of multiple genes" — in a murine model of hepatocellular carcinoma using in vivo R

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UK Royal Statistical Society is organizing a working group to develop guidelines for assessing COVID-19 tests, the Guardian reports.

The Washington Post reports that the White House chief of staff has asked the US Food and Drug Administration to justify the stricter standards it is seeking for a coronavirus vaccine.

President Donald Trump's "good genes" comment raises eugenics concerns, CNN reports.

In PLOS this week: genetic analysis of tremor condition, analysis of a West and Central African tree used in traditional medicine, and more.