This Week in PNAS

Using ChIP-seq to define TEAD4 target genes genome-wide to decipher how their transcription is maintained in the trophectoderm in a preimplantation mouse embryo model, a team led by researchers at the University of Kansas Medical Center found that a "lack of nuclear localization of TEAD4 impairs the TE [trophectoderm]-specific transcriptional program in inner blastomeres, thereby allowing their maturation toward the ICM [inner cell mass] lineage." In a paper published online in advance in

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.

In Science this week: reduction in bee phylogenetic diversity, and more.