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Using ChIP-seq to define TEAD4 target genes genome-wide to decipher how their transcription is maintained in the trophectoderm in a preimplantation mouse embryo model, a team led by researchers at the University of Kansas Medical Center found that a "lack of nuclear localization of TEAD4 impairs the TE [trophectoderm]-specific transcriptional program in inner blastomeres, thereby allowing their maturation toward the ICM [inner cell mass] lineage." In a paper published online in advance in

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Russia says its candidate SARS-CoV-2 vaccine has a very high efficacy rate in an initial analysis of clinical trial data, according to the Financial Times.

Wired reports on a microbial analysis of sketches drawn by Leonardo DaVinci.

A new survey explores coronavirus vaccine hesitancy among Black and Latino individuals, the Washington Post reports.

In Nucleic Acids Research this week: the Aging Atlas database, a database of human metagenome-related metadata, and more.