This Week in PNAS

In a paper appearing in this week's Early Edition, researchers at Johns Hopkins University School of Medicine and at the University of California, Irvine, show that deletion of Lhx2 in aging mice induces constitutive reactive gliosis, which then reduces "rates of ongoing apoptosis and compromised both rod and cone photoreceptor function." The Hopkins-Irvine team adds that these animals also "showed a dramatically reduced ability to induce expression of secreted neuroprotective factors and displayed enhanced rates of apoptosis in light-damage assays." Overall, the researchers say their study

To read the full story....

Register for Free.

...and receive Daily News bulletins.

Already have an account?
Login Now.

Women with breast or ovarian cancer living in medically underserved regions of the US are less likely to get recommended BRCA1 or BRCA2 genetic testing, according to a new study.

Three immunology researchers are to receive this year's Albany Medical Center Prize in Medicine and Biomedical Research, the Albany Times-Union reports.

In Genome Research this week: clonal evolution analysis of acute myeloid leukemia, computational pipeline to examine relationships between bacterial pathogens, and more.

Elephants may have "re-animated" a pseudogene to help stave off cancer, according to the New York Times.