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Researchers at the University of California, Berkeley, identify two regions of the double-pleckstrin homology domain architecture of Rtt106 that mediate histone binding, as they report in the PNAS Early Edition this week. "When histone binding was compromised, Rtt106 localized properly to chromatin but failed to deliver H3K56ac, leading to replication and silencing defects," the Berkeley team found.

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Two COVID-19 vaccine developers have released their trial protocols to build public trust, the New York Times reports.

A new analysis finds the rapid COVID-19 test from DnaNudge to be highly accurate, Reuters reports.

In Science this week: global citizens' assembly on genome-editing technologies proposed, epigenetic markers predict metformin response, and more.

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