This Week in PNAS: Nov 22, 2011

Nov 22, 2011

In this week's PNAS Early Edition, the University of Alberta's Ling-ju Lin and Michael Schultz discuss promoter-targeted Rtt109 repression of ARG1 via "silencing a pathway of transcriptional activation that depends on ASF1." Lin and Schultz show that the intensity of ARG1 transcription "at its induced and repressed set points is controlled by different mechanisms of functional interplay between Rtt109 and Asf1."

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