This Week in PNAS

In this week's PNAS Early Edition, a team led by investigators at Cold Spring Harbor Laboratory in New York shows that "mice harboring deletion of the chromosomal region corresponding to 16p11.2 as well as mice harboring the reciprocal duplication," show dosage-dependent changes in "gene expression, viability, brain architecture, and behavior." The team says its study shows that 16p11.2 copy-number variants provide "insight into human neurodevelopmental disorders," like autism.

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Science speaks with the University of Michigan's Jedidiah Carlson, who has tracked population genetic discussions at white nationalist sites.

Gene therapies could qualify for a faster US Food and Drug Administration approval process, according to Stat News.

NPR reports that the US House of Representatives has passed a bill to enable terminally ill patients access to experimental drugs.

In Genome Research this week: inversion variants mapped in human, non-human primate genomes; transcriptome profiling of maize, sorghum; and more.