This Week in PNAS | GenomeWeb

This Week in PNAS

In this week's PNAS Early Edition, a team led by investigators at Cold Spring Harbor Laboratory in New York shows that "mice harboring deletion of the chromosomal region corresponding to 16p11.2 as well as mice harboring the reciprocal duplication," show dosage-dependent changes in "gene expression, viability, brain architecture, and behavior." The team says its study shows that 16p11.2 copy-number variants provide "insight into human neurodevelopmental disorders," like autism.

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The White House has created a list of cuts, including to the NIH, that could be in a budget bill for this year.

The US National Institutes of Health is to allow applicants to cite preprints just as they would any other research paper, ScienceInsider reports.

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In PNAS this week: tool to track transcriptome-wide binding, evidence of balancing selection on behavior-linked genes, and more.