This Week in PNAS

In this week's PNAS Early Edition, the University of Washington's Jay Shendure and his colleagues report on their exome sequencing study of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas, through which they uncovered a "spectrum of mutation frequencies in advanced and lethal prostate cancers." The team shows that "point mutations arising in coding regions of advanced prostate cancers are common but, with notable excepti

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.