This Week in PNAS

In this week's PNAS Early Edition, the University of Washington's Jay Shendure and his colleagues report on their exome sequencing study of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas, through which they uncovered a "spectrum of mutation frequencies in advanced and lethal prostate cancers." The team shows that "point mutations arising in coding regions of advanced prostate cancers are common but, with notable excepti

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Polygamy amplified a rare genetic disease in area near Arizona-Utah border, BBC Future reports.

Genetic ancestry testing led one woman to learn that her father and another baby boy had been switched at birth, the Washington Post reports.

Simple de-identification methods can protect information in a database from attackers, a new study suggests.

In Science this week: approach to visualize chromatin structure in nuclei, and more.