This Week in PNAS

Investigators at the University of British Columbia this week present in the PNAS Early Edition "a fully integrated microfluidic device capable of performing high-precision RT-qPCR measurements of gene expression from hundreds of single cells per run." The UBC team says its "device executes all steps of single-cell processing, including cell capture, cell lysis, reverse transcription, and quantitative PCR" with higher throughput, increased sensitivity, decreased measurement noise, a

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The US Food and Drug Administration has approved Alnylam's RNAi-based therapy Onpattro, according to Stat News.

Harvard Medical School's Seth Cassel and Cigall Kadoch argue in a Baltimore Sun op-ed that the recent TAILORx trial shows the potential of genomic-based medicine.

Researchers in the UK are working on using gene drives to control malaria-carrying mosquitoes, the Telegraph reports.

In PLOS this week: genetic architecture mediating gene expression, metabolomic patterns in multiple myeloma, and more.