This Week in PNAS

In a paper published online in advance in the PNAS Early Edition this week, a team led by investigators at Harvard Medical School shows that, in a mouse model of pancreatic neuorendocrine cancer, administration of the endogenous angiogenesis inhibitors endostatin, thrombospondin-1, and tumstatin peptides, "as well as deletion of their genes, reveal neoplastic stage-specific effects on angiogenesis, tumor progression, and survival, correlating with endothelial expression of their receptors." Further, the team reports its finding that the deletion of tumstatin and thrombospondin-1 in

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CNBC reports that Amazon invested in the startup Grail as it sees an opportunity for its cloud computing company in genomics.

Lawrence Krauss writes at Slate that science is needed for good public policy and should not be ignored.

Researchers are working on re-making the yeast genome from scratch, according to the Associated Press.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.