This Week in PNAS

In a paper published online in advance in the PNAS Early Edition this week, a team led by investigators at Harvard Medical School shows that, in a mouse model of pancreatic neuorendocrine cancer, administration of the endogenous angiogenesis inhibitors endostatin, thrombospondin-1, and tumstatin peptides, "as well as deletion of their genes, reveal neoplastic stage-specific effects on angiogenesis, tumor progression, and survival, correlating with endothelial expression of their receptors." Further, the team reports its finding that the deletion of tumstatin and thrombospondin-1 in

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.