This Week in PNAS

In this week's PNAS Early Edition, a team led by investigators at Cardiff University shows that "combining disease 'risk' variants in add-back assays yielded six-fold higher hemolytic activity compared with 'protective' variants" in their investigations of age-related macular degeneration.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.