This Week in PNAS

In the PNAS Early Edition this week, researchers in Massachusetts model high-grade serous ovarian carcinogenesis from the fallopian tubes. Most ovarian cancer research is based on the notion that high-grade serous ovarian carcinoma arises from the ovarian surface epithelial cells, the authors write, though recent studies suggest that almost 50 percent of these carcinomas likely arise from fallopian tube epithelium.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more