This Week in PNAS

In the PNAS Early Edition this week, Stephen Quake and his colleagues at Stanford University report their development of a universal, non-invasive approach to monitor the health of transplanted organs that uses high-throughput shotgun sequencing to detect donor cell-free DNA circulating in recipients' blood. Quake et al.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.