This Week in PNAS

In the PNAS Early Edition this week, investigators at the DDC Clinic for Special Needs Children in Middleton, Ohio, "describe an autosomal recessive condition characterized with cerebral vasculopathy and early onset of stroke in 14 individuals in Old Order Amish." Using candidate gene sequencing, they found that the condition is caused by a homozygous mutation in the SAMHD1 gene.

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An artificial intelligence-based analysis suggests a third group of ancient hominins likely interbred with human ancestors, according to Popular Mechanics.

In Science this week: reduction in bee phylogenetic diversity, and more.

The New York Times Magazine looks into paleogenomics and how it is revising what's know about human history, but also possibly ignoring lessons learned by archaeologists.

The Economist reports on Synthorx's efforts to use expanded DNA bases they generated to develop a new cancer drug.