This Week in PNAS | GenomeWeb

This Week in PNAS

Scientists at SUNY Buffalo have addressed addiction using nanotechnology and siRNA. Their approach used gold nanorod-siRNA silencing complexes that target the dopaminergic signaling pathway in the brain, and induced reduced expression of DARPP-32, ERK, and PP-1. These nanoplexes "appear to be suited for brain-specific delivery of appropriate siRNA for therapy of drug addiction and other brain diseases," they write.

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In PLOS this week: nasal microbial communities in asthma patients; sequencing-based way to detect, track schistosomiasis; and more.

The New York Times speaks with Vanderbilt's John Anthony Capra about Neanderthal genes in modern humans.

A draft guidance from the FDA suggests the agency wants to more tightly control gene-edited animals, according to Technology Review.

Researchers were among this weekend's protesters bemoaning the new US administration, Vox reports.