This Week in PNAS

Scientists at SUNY Buffalo have addressed addiction using nanotechnology and siRNA. Their approach used gold nanorod-siRNA silencing complexes that target the dopaminergic signaling pathway in the brain, and induced reduced expression of DARPP-32, ERK, and PP-1. These nanoplexes "appear to be suited for brain-specific delivery of appropriate siRNA for therapy of drug addiction and other brain diseases," they write.

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The UK's Human Fertility and Embryology Authority calls for consumer genetic testing companies to warn customers that testing could uncover family secrets, according to the Guardian.

The New York Times reports that United Nations delegates have been discussing how to govern the genetic resources of the deep sea.

Researchers have transplanted edited cells into mice that appear to combat cocaine addiction, New Scientist reports.

In PNAS this week: analysis of proteolytic enzymes secreted by circulating tumor cells, phylogenetic study of Fv1 evolution, and more.

Nov
05
Sponsored by
Sophia Genetics

With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.