This Week in PNAS

In early online publication this week, scientists used microfluidic cards to profile miRNA expression in kidney transplants. They profiled seven renal allograft biopsies against 365 miRNAs and performed control expression analysis on 26 other transplants, finding a strong association between intragraft expression of both miRNAs and mRNAs and that acute rejection "could be predicted with a high level of precision using intragraft levels of miRNAs," they write in the abstract.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.