This Week in PLoS

In PLoS Biology this week, investigators at St. Jude Children's Research Hospital show that the homeobox gene "Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis." Specifically, Prox1 — expressed in the dentate gyrus during embryonic development and adult neurogenesis — is expressed in intermediate progenitors, and "required for adult neural stem cell self-maintenance in the sub-granular zone," the authors write.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.