This Week in PLoS

In PLoS One this week, investigators at McGill University report their use of exon-level transcriptome profiling in murine breast cancer, which revealed "splicing changes specific to tumors with different metastatic abilities." Specifically, in their statistical analysis the team found "significant expression changes in four percent of exons and one percent of intronic regions, affecting 2,263 out of 16,654 genes.

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An opinion piece in the Guardian argues that President Donald Trump is uninterested in science and that might not be a bad thing for the field.

The San Francisco Chronicle reports the Veterans Affairs Health System is studying whether genetic testing can help prescribe better depression therapies.

Stat News reports that Spark Therapeutics' Luxturna is now being used to treat a wider array of patients.

In Genome Biology this week: transcription factor use among brittle stars, single-cell RNA sequencing strategy, and more.