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In PLoS One this week, an international research team reports the "variability in the incidence of miRNAs and genes in fragile sites and the role of repeats and CpG islands in the distribution of genetic material," which they've elucidated using statistical models. The researchers found that fragile sites are denser in miRNAs on average, and that there's a "positive correlation between fragility and repeats, and between miRNAs and CpG islands."

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In PLOS this week: recessive mutation tied to early-onset dilated cardiomyopathy, epigenetic analysis of lung adenocarcinoma, and more.