This Week in PLoS

In PLoS Biology this week, investigators at the University of Toronto report that most "dark matter" transcripts are associated with known genes in the mouse and human genomes. Using a combination of RNA-seq information and data obtained from tiling arrays experiments, the team shows that most of the seqfrags — or transcribed regions outside known exons and non-coding RNAs — are within introns, "raising the possibility that they are fragments of pre-mRNAs," they write.

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The New York City medical examiner is overseeing an effort to identify missing persons using DNA, according to the Associated Press.

Nobel laureate Günter Blobel has died at 81, the New York Times reports.

In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.

Technology Review reports that 2017 was the year of consumer genetic testing and that it could spur new analysis companies.