In PLoS Genetics this week, a trio of researchers from the University of California, San Diego, report that post-replication repair "prevents replication damage from becoming double strand breaks and/or regulates the activity of HR [homologous recombination] on DSBs." Namely, by investigating RAD6 and RAD18-dependent post-replication repair, the team found that "the RAD5-, MMS2-, [and] UBC13-dependent error-free PRR branch acted in concert with the replication stress checkp