This Week in PLoS

In PLoS One this week, researchers from six US institutions report the results of their genome-wide association study that identifies GPC5 as a novel genetic locus that is protective against sudden cardiac arrest. Using a case-control design with participants from the Oregon Sudden Unexpected Death Study, and, while no SNPs identified reached genome-wide significance, the minor allele of GPC5 showed an association with a lower risk of SCA.

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Rare gene mutations are guiding the search for drugs to manage chronic pain without opioids, according to CNBC.

The new Francis Crick Institute building can get too noisy for some researchers to concentrate, according to the Guardian.

CBS News reports that there are still many vacancies at the White House Office of Science and Technology Policy, but that it's uncertain whether they will be filled.

In Nucleic Acids Research this week: pipeline to analyze and visualize bacterial genomes, database of global set of human genomes, and more.