This Week in PLoS | GenomeWeb

This Week in PLoS

In PLoS Biology this week, Duke University researcher David Goldstein and his co-workers report that "synthetic associations" between rare and common variants may be behind the results of some genome-wide association studies. The conclusion is based on the team's simulation experiments as well as GWAS of sickle cell anemia and hearing loss. "[E]ven those signals that have been detected for common variants could, in principle, come from the effect of rare ones," they write.

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A Karmagenes researcher has lost his position after reportedly admitting to data fabrication, according to Retraction Watch.

Two neuroscientists write in Nature News that solving the "reproducibility crisis" in science may require changing the requirements for publication.

In Nature this week: genomic analysis of prehistoric New Mexicans, a nanopore method for mapping DNA methylation, and more.

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