This Week in PLoS

Scientists have added more than 10 percent new genes to the yeast ribosome biogenesis pathway in work appearing this week in PLoS Biology. Zhihua Li at the University of Texas, Austin, is first author on a paper that used network-guided genetics, "an approach for associating candidate genes with biological processes that capitalizes on recent advances in functional genomic and proteomic studies," to identify additional ribosomal biogenesis genes, says the abstract.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.