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Scientists have added more than 10 percent new genes to the yeast ribosome biogenesis pathway in work appearing this week in PLoS Biology. Zhihua Li at the University of Texas, Austin, is first author on a paper that used network-guided genetics, "an approach for associating candidate genes with biological processes that capitalizes on recent advances in functional genomic and proteomic studies," to identify additional ribosomal biogenesis genes, says the abstract.

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