This Week in PLoS | GenomeWeb

This Week in PLoS

In an effort to speed up the drug discovery process for multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis, UCSD's Philip Bourne led work that used a proteomic, computational approach to identify cross-reactivity between different drug target families. The team showed that entacapone and tolcapone, two drugs used to treat Parkinson's disease, can also help treat MDR and XDR tuberculosis. The work appears in PLoS Computational Biology this week.

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In Science this week: genetic target for urothelial bladder cancer treatment, and more.

At the Conversation, the University of Oxford's Michael Macklay writes that learning genetic risk of disease is a personal decision.

Two dozen scientific organizations have endorsed the March for Science, according to ScienceInsider.

Researchers in Japan describe a chimpanzee with a chromosomal abnormality similar to human Down syndrome, Mashable reports.