This Week in PLoS

In an effort to speed up the drug discovery process for multi-drug resistant (MDR) and extensively drug resistant (XDR) tuberculosis, UCSD's Philip Bourne led work that used a proteomic, computational approach to identify cross-reactivity between different drug target families. The team showed that entacapone and tolcapone, two drugs used to treat Parkinson's disease, can also help treat MDR and XDR tuberculosis. The work appears in PLoS Computational Biology this week.

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Berkeley researchers have engineered yeast to make the molecule behind the hoppy taste of beer, Quartz reports.

King's College London researchers examine the influence of school type and genetics on academic achievement.

FiveThirtyEight writes that most who take a direct-to-consumer BRCA1/2 genetic test won't learn much from it.

In Science this week: early life experience influence somatic variation in the genome, and more.