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In PLoS Computational Biology this week, Michael Brudno published his short read aligner, SHRiMP, or SHort Read Mapping Package, which is a "set of algorithms and methods to map short reads to a genome, even in the presence of a large amount of polymorphism." The software is based on a fast read mapping technique for both regular letter-space and AB SOLiD, or color-space, reads.

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