This Week in PLOS

In PLOS Genetics, the National Cancer Institute's Javed Khan and colleagues from the US, Australia, Spain, and Italy used whole-genome sequencing, targeted gene sequencing, and transcriptome sequencing to characterize 65 Ewing sarcoma tumors and three dozen cell lines.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.