This Week in PLOS

Transcriptional patterns found in human induced pluripotent stem cell lines hinge on the genetic background of the human iPS cells, according to a PLOS Genetics study by researchers at the Wellcome Trust Sanger Institute. The team performed RNA sequencing on more than two dozen iPS cell lines generated from the same types of somatic tissues from several different donors.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.