This Week in PLOS | GenomeWeb

This Week in PLOS

The University of Pennsylvania's Hakon Hakonarson and colleagues used transcriptome profiles of colonic mucus to look for gene expression shifts associated with ulcerative colitis. As they report in PLOS One, the investigators relied on a gene set enrichment analysis approach to assess three sets of gene expression data generated on endoscopic colon biopsy samples with microarrays.

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Harold Varmus, a former NIH director, says that proposed reductions to the agency's budget are worrisome.

The Genome 10K project is to sequence about 10,000 vertebrate genomes, including ones of endangered species, Digital Trends reports.

The new Coalition to Save NIH Funding aims to educate lawmakers and the public on the significance of biomedical research.

In PLOS this week: analysis of viral sequences from human blood samples, gut microbiomes of heart failure patients, and more.